|
KMID : 0356919940270010060
|
|
Korean Journal of Anesthesiology
1994 Volume.27 No. 1 p.60 ~ p.65
|
|
|
Induced Hypotension by Labetalol during Spine Surgery
|
|
|
|
|
Abstract
|
|
|
The effect of labetalol on induced hypotension was studied in 13 patients undergoing major spine surgery. Hypotension was induced with initial dose of labetalol 0.4 mg/kg i.v. followed by 0.01 mg/kg/min i.v.infusion. BP, HR, and CVP were measured
before, during, and after hypotension. Anesthesia was maintained with isoflurane (0.5-2 vo1%) and N2O in 50% O2 supplemented by pancuronium.
The time to systolic BP 75-85 mmHg or mean BP 55-65 mmHg was 18.5±2.8min and the time for systolic BP to recover 90% of prehypotensive vale was 45.5±4.2 min. Heart rate was reduced significantly after hypotension but remained stable at 80-90
beats/min
thereafter. Central venous pressure showed mo significant change irrespective of hypotension. The results suggest that combined use of fentany! or disuse of pancuronium may reduce the required dose of labetalol.
|
|
|
KEYWORD
|
|
|
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
   
|